CA 19-9 is a tumor marker most commonly elevated in which cancer?

Study for the NBME Form 13 Test with our comprehensive quiz collection, featuring flashcards and multiple-choice questions to ensure your readiness. Enhance your knowledge with detailed explanations for each question.

Multiple Choice

CA 19-9 is a tumor marker most commonly elevated in which cancer?

Explanation:
CA 19-9 is a tumor marker most closely linked to pancreatic cancer. In practice, levels are often elevated in pancreatic adenocarcinoma and can be helpful in monitoring treatment response or detecting recurrence, though it isn’t perfect for screening and can be raised in other biliary or GI conditions. The other markers correspond to different cancers: CEA more often rises with colorectal and other GI cancers; AFP with hepatocellular carcinoma and some germ cell tumors; CA-125 with ovarian cancer. So, among the options, CA 19-9 best fits pancreatic cancer.

CA 19-9 is a tumor marker most closely linked to pancreatic cancer. In practice, levels are often elevated in pancreatic adenocarcinoma and can be helpful in monitoring treatment response or detecting recurrence, though it isn’t perfect for screening and can be raised in other biliary or GI conditions. The other markers correspond to different cancers: CEA more often rises with colorectal and other GI cancers; AFP with hepatocellular carcinoma and some germ cell tumors; CA-125 with ovarian cancer. So, among the options, CA 19-9 best fits pancreatic cancer.

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