What is the effect of supervised exercise programs on claudication symptoms in peripheral artery disease?

• A. They worsen claudication
• B. They have no effect
• C. They reduce symptoms of claudication
• D. They are contraindicated

Answer: (C)

Supervised exercise programs reduce claudication symptoms in peripheral artery disease by training the leg muscles to work more efficiently under reduced blood flow. Regular walking prompts adaptations such as improved endothelial function, increased capillary density, and better skeletal muscle oxidative capacity. These changes enhance muscle perfusion during effort and improve walking economy, allowing a person to walk longer before pain begins and to sustain activity longer overall. Because of these benefits, supervised exercise is a first-line therapy for intermittent claudication and is not a contraindication; the program is typically structured, progressive treadmill walking several times a week to maximize functional improvement.