Which autoantibody is commonly present and highly specific for type 1 diabetes?

Unlock all questions

This demo includes only 20 questions. Upgrade to access hundreds of questions, flashcards, exam simulations, and disable ads.

Full question bankExam simulationsFlashcards
From $25.99Unlock all

Study for the NBME Form 13 Test with our comprehensive quiz collection, featuring flashcards and multiple-choice questions to ensure your readiness. Enhance your knowledge with detailed explanations for each question.

Multiple Choice

Which autoantibody is commonly present and highly specific for type 1 diabetes?

Explanation:
Autoimmune destruction of pancreatic beta cells often shows up with specific autoantibodies, and the most commonly detected, highly specific one in type 1 diabetes targets GAD-65. GAD-65 is an enzyme in beta cells, and autoantibodies against it are frequently present at diagnosis and help distinguish autoimmune diabetes from other forms. While other autoantibodies like IA-2, islet cell cytoplasmic antibodies, or insulin autoantibodies can be seen, they are either less consistently present or less specific, making GAD-65 the best marker in this context.

Autoimmune destruction of pancreatic beta cells often shows up with specific autoantibodies, and the most commonly detected, highly specific one in type 1 diabetes targets GAD-65. GAD-65 is an enzyme in beta cells, and autoantibodies against it are frequently present at diagnosis and help distinguish autoimmune diabetes from other forms. While other autoantibodies like IA-2, islet cell cytoplasmic antibodies, or insulin autoantibodies can be seen, they are either less consistently present or less specific, making GAD-65 the best marker in this context.

More Multiple Choice Questions
Subscribe

Get the latest from Passetra

You can unsubscribe at any time. Read our privacy policy